Patent(s):
 
2015-04-09
 
Thomas Haas, Jan Christoph Pfeffer, Jan Christoph Pfeffer, Arne Skerra, Alexandra Lerchner, Alexander Jarasch & EVONIK industries AG
NADP-DEPENDENT ALANINE DEHYDROGENASE
Patent application number: 20150099282
 
Publication(s):
 
2016
 
Jarasch A. and Skerra A.
Aligning, analyzing, and visualizing sequences for antibody engineering: Automated recognition of immunoglobulin variable region features.
Proteins. 2016 Oct 22.
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Lerchner A, Daake M., Jarasch A and Skerra A.
Fusion of an alcohol dehydrogenase with an aminotransferase using a PAS linker to improve coupled enzymatic alcohol-to-amine conversion.
Protein Eng Des Sel., Aug 29, 2016
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Jarasch A, Kopp M., Eggenstein E., Richter A. Gebauer M. and Skerra A.
ANTICALIgN: visualizing, editing and analyzing combined nucleotide and amino acid sequence alignments for combinatorial protein engineering.
Protein Eng Des Sel. 2016 Jul;29.
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2015
 
Lerchner A, Jarasch A, Skerra A.
Engineering of alanine dehydrogenase from Bacillus subtilis for novel cofactor specificity.
Biotechnol Appl Biochem. 2015 Jul 23.
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Jarasch A, Koll H, Regula JT, Bader M, Papadimitriou A, Kettenberger H.
Developability assessment during the selection of novel therapeutic antibodies.
J Pharm Sci. 2015 Jun
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2013
 
Lerchner A., Jarasch A,, , Meining W., Schiefner A. and Skerra A.
Crystallographic Analysis and structure-guided engineering of NADPH-dependent Ralstonia sp. Alcohol dehydrogenase toward NADH cosubstrate specificity.
Biotechnol Bioeng. 2013 May 18
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2012
 
Jarasch A, Dziuk P, Becker T, Armache JP, Hauser A, Wilson DN, Beckmann R.
The DARC site: a database of aligned ribosomal complexes.
Nucleic Acids Res. 2012 Jan
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Awarded to the top 5% of NAR papers in terms of originality, significance and scientific excellence.
 
2011
 
Becker T, Armache JP, Jarasch A, Anger AM, Villa E, Sieber H, Motaal BA, Mielke T, Berninghausen O, Beckmann R.
Structure of the no-go mRNA decay complex Dom34-Hbs1 bound to a stalled 80S ribosome.
NSMB. 2011 Jun;18.
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Alexander Jarasch:
3D modeling of ribosomal RNA using cryo-electron microscopy density maps
Dissertation thesis 2011
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2010
 
Armache JP *, Jarasch A *, Anger AM *, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Söding J, Westhof E, Wilson DN, Beckmann R.
Cryo-EM structure and rRNA model of a translating eukaryotic 80S ribosome at 5.5-Å resolution
PNAS USA. 2010 Oct 27.
Open access Click here
 
Armache JP *, Jarasch A *, Anger AM *, Villa E, Becker T, Bhushan S, Jossinet F, Habeck M, Dindar G, Franckenberg S, Marquez V, Mielke T, Thomm M, Berninghausen O, Beatrix B, Söding J, Westhof E, Wilson DN, Beckmann R.
Localization of eukaryote-specific ribosomal proteins in a 5.5-Å cryo-EM map of the 80S eukaryotic ribosome.
PNAS USA. 2010 Oct 25.
Open access Click here
 
Bhushan S, Gartmann M, Halic M, Armache JP, Jarasch A, Mielke T, Berninghausen O, Wilson DN, Beckmann R.
alpha-Helical nascent polypeptide chains visualized within distinct regions of the ribosomal exit tunnel.
NSMB, 2010 Mar
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2009
 
Thomas Becker, Elisabet Mandon, Shashi Bhushan, Alexander Jarasch, Jean-Paul Armache, Soledad Funes, Fabrice Jossinet, James Gumbart, Thorsten Mielke, Otto Berninghausen, Klaus Schulten, Eric Westhof, Reid Gilmore, and Roland Beckmann
Structure of monomeric yeast and mammalian Sec61 complexes interacting with the translating ribosome
Science, 2009 Dec 4.
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2007
 
Alexander Jarasch:
Similarity-based analysis of medium- and highthroughput screening data.
Diploma thesis 2007 pdf (A4 paper); BibTex
 
2006
 
Kramer, S, Aufschild, V, Hapfelmeier, A, Jarasch, A, Kessler, K, Reckow, S, Wicker, J, and Richter, L (2006).
Inductive Databases in the Relational Model: The Data as the Bridge
In: Proceedings of the Fourth International Workshop on Knowledge Discovery in Inductive Databases
(KDID-2005), pp. 124-138.